Heat-shock response in cultured chick embryo chondrocytes. Osteonectin is a secreted heat-shock protein
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چکیده
منابع مشابه
A major collagen-binding protein of chick embryo fibroblasts is a novel heat shock protein
Heat shock proteins of chick embryo fibroblasts were analyzed on SDS polyacrylamide gradient gels and were found to include not only three previously well-characterized proteins of 25,000, 73,000, and 89,000 D, but also a 47,000-D protein. Two-dimensional gel electrophoresis revealed that this protein was unusually basic (pI = 9.0) and corresponded to a recently characterized, major gelatin- an...
متن کاملHeat shock causes repeated segmental anomalies in the chick embryo.
A single heat shock, given to 2-day-old chick embryos, can generate multiple but discrete somite and skeletal anomalies. Each of these anomalies is restricted to one, or at the most two, consecutive segments. The anomalies are separated from each other by a distance of 6-7 somites or vertebrae, or a multiple of this distance. These results argue against the 'clock and wavefront' model; while th...
متن کاملRegulation of heat shock protein 70 synthesis by heat shock in the preimplantation murine embryo.
Induced thermotolerance in murine embryos occurs at the 8-cell stage when embryos are maintained in vitro but not until the blastocyst stage if development proceeds in vivo. Present results indicate that ability of embryos to undergo induced thermotolerance is not limited by heat shock protein 70 (HSP70) synthesis. Exposure of 8-cell embryos to 40 degrees C enhanced synthesis of 2 constitutive ...
متن کاملThe heat-shock response.
PERSPECTIVES AND SUMMARY .............................................................. 1151 CHARACTERIZATION OF THE RESPONSE .................................................. 1153 Comparison: Different Organisms and Stages of Development ........................... 1153 The Proteins Induced by Heat .................................................................. 1155 RNAs Induced by Heat .....
متن کاملInduction of thermotolerance and heat shock protein synthesis in normal and respiration-deficient chick embryo fibroblasts.
Normal and transformed chick embryo cells and their respective ethidium bromide-treated derivatives that are devoid of a functional respiratory chain were comparatively evaluated for their responses to hyperthermia treatment. No significant difference was found between the control and the respiration-deficient cells. The cells have a similar intrinsic thermosensitivity as judged by their capaci...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1992
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1992.tb16814.x